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Interleukin-1 alpha (rs1800587) genetic polymorphism is associated with specific cognitive functions but not depression or loneliness in elderly males without dementia.

Neuroscience letters - 27 Nov 2013

Wang Eileen H, Hong Chen-Jee, Yeh Heng-Liang, Liou Ying-Jay, Yang Albert C, Liu Mu-En, Tsai Shih-Jen

Abstract excerpt

Inflammatory process is considered to be a pathway that results in neurodegeneration, and numerous plasma cytokines have been examined for their association with cognitive function and depression. Interleukin-1 alpha (IL-1A) genetic polymorphism (rs1800587) has been found to be associated with Alzheimer's disease susceptibility. The aim of this study was to investigate the effect of IL-1A rs1800587 genetic...

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PMID: 24103372
DOI: 10.1016/j.neulet.2013.09.057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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