Article
Heritabilities, proportions of heritabilities explained by GWAS findings, and implications of cross-phenotype effects on PR interval.
Human genetics - 1 Nov 2015
Silva Claudia Tamar, Kors Jan A, Amin Najaf, Dehghan Abbas, Witteman Jacqueline C M, Willemsen Rob, Oostra Ben A, van Duijn Cornelia M, Isaacs Aaron
Abstract excerpt
Electrocardiogram (ECG) measurements are a powerful tool for evaluating cardiac function and are widely used for the diagnosis and prediction of a variety of conditions, including myocardial infarction, cardiac arrhythmias, and sudden cardiac death. Recently, genome-wide association studies (GWASs) identified a large number of genes related to ECG parameter variability, specifically for the QT, QRS, and PR...
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