Article
Heritability of early repolarization: a population-based study.
Circulation. Cardiovascular genetics - 1 Apr 2011
Reinhard Wibke, Kaess Bernhard M, Debiec Radoslaw, Nelson Christopher P, Stark Klaus, Tobin Martin D, Macfarlane Peter W, Tomaszewski Maciej, Samani Nilesh J, Hengstenberg Christian
Abstract excerpt
BACKGROUND: Early repolarization (ER), defined by J-point elevation in 12-lead ECG, was recently associated with increased risk for idiopathic ventricular fibrillation and cardiovascular mortality. The determinants of ER are unknown. We investigated its heritability in a large, family-based cohort. METHODS AND RESULTS: The study sample comprised 1877 individuals from 505 white nuclear families representative of...
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