FIV infection induces unique changes in phenotype and cellularity in the medial iliac lymph node and intestinal IEL.

Abstract excerpt

Studies of human immunodeficiency virus-1 (HIV-1)-infected patients and simian immunodeficiency virus (SIV)-infected macaques have identified profound depletion of CD4(+) T cells and expansion of CD8(+) T cells in the gastrointestinal lamina propria. Less attention has been given to CD8(+) intraepithelial lymphocytes (IEL), and no studies have concurrently examined inductive sites such as draining lymph nodes....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cats
• Share to CD4-Positive T-Lymphocytes
• Share to CD8-Positive T-Lymphocytes