Article
Functional Site-Directed Fluorometry.
Advances in experimental medicine and biology - 1 Jan 2015
Priest Michael, Bezanilla Francisco
Abstract excerpt
Initially developed in the mid-1990s to examine the conformational changes of the canonical Shaker voltage-gated potassium channel, functional site-directed fluorometry has since been expanded to numerous other voltage-gated and ligand-gated ion channels as well as transporters, pumps, and other integral membrane proteins. The power of functional site-directed fluorometry, also known as voltage-clamp fluorometry,...
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