Article
Assessing metabolic activity in aging Caenorhabditis elegans: concepts and controversies.
Aging cell - 1 Dec 2002
Braeckman Bart P, Houthoofd Koen, Vanfleteren Jacques R
Abstract excerpt
It is widely believed that normal by-products of oxidative metabolism and the subsequent molecular damage inflicted by them couple the aging process to metabolic rate. Accordingly, high metabolic rates would be expected to accelerate aging, and life-extending interventions are often assumed to act by attenuating metabolic rate. Notorious examples in Caenorhabditis elegans are food restriction, mutation in the...
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