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Article

Full-length soluble urokinase plasminogen activator receptor down-modulates nephrin expression in podocytes.

Scientific reports - 18 Sept 2015

Alfano Massimo, Cinque Paola, Giusti Guido, Proietti Silvia, Nebuloni Manuela, Danese Silvio, D'Alessio Silvia, Genua Marco, Portale Federica, Lo Porto Manuela, Singhal Pravin C, Rastaldi Maria Pia, Saleem Moin A, Mavilio Domenico, Mikulak Joanna

Abstract excerpt

Increased plasma level of soluble urokinase-type plasminogen activator receptor (suPAR) was associated recently with focal segmental glomerulosclerosis (FSGS). In addition, different clinical studies observed increased concentration of suPAR in various glomerular diseases and in other human pathologies with nephrotic syndromes such as HIV and Hantavirus infection, diabetes and cardiovascular disorders. Here, we...

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Identifiers

PMID: 26380915
DOI: 10.1038/srep13647
PMCID: PMC4585377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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