Back to search

Article

miR-204-5p Preserves Kidney Function by Protecting Nephrin from Enzymatic Degradation in a Nephrotoxic Serum Animal Model

2025-01-30

Abstract excerpt

Nephrin is an essential constituent of the slit-diaphragm of the kidney filtering unit. Loss of nephrin expression leads to protein leakage into the urine, one of the hallmarks of kidney damage. Autoantibodies against nephrin have been reported in patients with minimal change disease and recurrent focal segmental glomerulosclerosis. Understanding the mechanism of nephrin loss may help improve or lead to the develo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cf2c2a34-4760-51db-9a8d-c74b515feabd
DOI
10.20944/preprints202501.2295.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
miR-204-5p Preserves Kidney Function by Protecting Nephrin from Enzymatic Degradation in a Nephrotoxic Serum Animal ModelDOI 10.20944/preprints202501.2295.v1
microRNAs in glomerular diseases from pathophysiology to potential treatment target.Semantic proximity
Pathogenic Role of MicroRNA Dysregulation in PodocytopathiesSemantic proximity
An update: the role of Nephrin inside and outside the kidneySemantic proximity
Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous GlomerulonephritisSemantic proximity
Autoantibodies against nephrin elucidate a novel autoimmune phenomenon in proteinuric kidney diseaseSemantic proximity
MicroRNAs as Biomarkers for Nephrotic SyndromeSemantic proximity
Potential and pitfalls of measuring circulating anti-nephrin autoantibodies in glomerular diseasesSemantic proximity
Protein-losing nephropathy in small animals.Semantic proximity
MicroRNAs: a new avenue to understand, investigate and treat immunoglobulin A nephropathy?Semantic proximity
Unwinding focal segmental glomerulosclerosisSemantic proximity
The Spectrum of Minimal Change Disease/Focal Segmental Glomerulosclerosis: From Pathogenesis to Proteomic Biomarker ResearchSemantic proximity
miR-135a-5p in Exosomes Promotes Childhood Nephrotic Syndrome via GSK-3β and TGF-β1 CrosstalkSemantic proximity
Select a neighboring publication to make it the new centre.