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Article

A survey of tandem repeat instabilities and associated gene expression changes in 35 colorectal cancers.

BMC genomics - 16 Sept 2015

Sonay Tugce Bilgin, Koletou Malamati, Wagner Andreas

Abstract excerpt

BACKGROUND: Colorectal cancer is a major contributor to cancer morbidity and mortality. Tandem repeat instability and its effect on cancer phenotypes remain so far poorly studied on a genome-wide scale. RESULTS: Here we analyze the genomes of 35 colorectal tumors and their matched normal (healthy) tissues for two types of tandem repeat instability, de-novo repeat gain or loss and repeat copy number variation....

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Share to DNA Copy Number Variations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

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Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 26376692
DOI: 10.1186/s12864-015-1902-9
PMCID: PMC4574073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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