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Multicancer analyses of short tandem repeat variations reveal shared gene regulatory mechanisms

2025-01-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Short tandem repeats (STRs) have been reported to influence gene expression across various human tissues. While STR variations are enriched in colorectal (CRC), stomach (STAD) and endometrial (UCEC) cancers, particularly in microsatellite instable (MSI) tumors, their functional effects and regulatory mechanisms on gene expression remain poorly understood across t...

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Literature Corpus work: 02c7645a-e8d0-56df-9c87-d42acb324391
DOI: 10.21203/rs.3.rs-5775561/v1

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