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Article

Temperature Sensitivity of Neural Tube Defects in Zoep Mutants.

Zebrafish - 1 Dec 2015

Ma Phyo, Swartz Morgan R, Kindt Lexy M, Kangas Ashley M, Liang Jennifer Ostrom

Abstract excerpt

Neural tube defects (NTD) occur when the flat neural plate epithelium fails to fold into the neural tube, the precursor to the brain and spinal cord. Squint (Sqt/Ndr1), a Nodal ligand, and One-eyed pinhead (Oep), a component of the Nodal receptor, are required for anterior neural tube closure in zebrafish. The NTD in sqt and Zoep mutants are incompletely penetrant. The penetrance of several defects in sqt mutants...

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Identifiers

PMID: 26366681
DOI: 10.1089/zeb.2015.1113
PMCID: PMC4677512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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