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Article

Environmental and genetic modifiers of squint penetrance during zebrafish embryogenesis.

Developmental biology - 15 Aug 2007

Pei Wuhong, Williams P Huw, Clark Matthew D, Stemple Derek L, Feldman Benjamin

Abstract excerpt

The Nodal-related subgroup of the TGFbeta superfamily of secreted cytokines regulates the specification of the mesodermal and endodermal germ layers during gastrulation. Two Nodal-related proteins - Squint (Sqt) and Cyclops (Cyc) - are expressed during germ-layer specification in zebrafish. Genetic sqt mutant phenotypes have defined a variable requirement for zygotic Sqt, but not for maternal Sqt, in midline...

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Identifiers

PMID: 17583692
DOI: 10.1016/j.ydbio.2007.05.026
PMCID: PMC1994576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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