Article
A recessive lethal mutation, tb, that bends the midbrain region of the neural tube in the early embryo of the medaka.
Neuroscience research - 1 Feb 1996
Ishikawa Y
Abstract excerpt
A recessive lethal mutation, tb (twisted brain), in the homozygous embryo of which the neural tube is twisted, was newly found in the medaka (Oryzias latipes). The mutation was recovered in the progeny of a male medaka which had been treated with N-ethyl-N-nitrosourea (ENU). The mutation affected morphogenic cell movements (extension and convergence) in the gastrula and neurula stages. In these stages, the...
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