Article
Zebrafish organizer development and germ-layer formation require nodal-related signals.
Nature - 10 Sept 1998
Feldman B, Gates M A, Egan E S, Dougan S T, Rennebeck G, Sirotkin H I, Schier A F, Talbot W S
Abstract excerpt
The vertebrate body plan is established during gastrulation, when cells move inwards to form the mesodermal and endodermal germ layers. Signals from a region of dorsal mesoderm, which is termed the organizer, pattern the body axis by specifying the fates of neighbouring cells. The organizer is it...
Topics
- Amino Acid Sequence
- Animals
- Blastocyst
- Body Patterning
- Chromosome Mapping
- Embryonic Induction
- Gastrula
- Germ Layers
- Goosecoid Protein
- Homeodomain Proteins
- Intracellular Signaling Peptides and Proteins
- Molecular Sequence Data
- Mutation
- Nodal Signaling Ligands
- Ovum
- Repressor Proteins
- Signal Transduction
- Transcription Factors