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Article

Nodal signaling is required for closure of the anterior neural tube in zebrafish.

BMC developmental biology - 8 Nov 2007

Aquilina-Beck Allisan, Ilagan Kristine, Liu Qin, Liang Jennifer O

Abstract excerpt

BACKGROUND: Nodals are secreted signaling proteins with many roles in vertebrate development. Here, we identify a new role for Nodal signaling in regulating closure of the rostral neural tube of zebrafish. RESULTS: We find that the neural tube in the presumptive forebrain fails to close in zebrafish Nodal signaling mutants. For instance, the cells that will give rise to the pineal organ fail to move from the...

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Identifiers

PMID: 17996054
DOI: 10.1186/1471-213X-7-126
PMCID: PMC2214732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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