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Article

Metalloprotease OMA1 Fine-tunes Mitochondrial Bioenergetic Function and Respiratory Supercomplex Stability.

Scientific reports - 14 Sept 2015

Bohovych Iryna, Fernandez Mario R, Rahn Jennifer J, Stackley Krista D, Bestman Jennifer E, Anandhan Annadurai, Franco Rodrigo, Claypool Steven M, Lewis Robert E, Chan Sherine S L, Khalimonchuk Oleh

Abstract excerpt

Mitochondria are involved in key cellular functions including energy production, metabolic homeostasis, and apoptosis. Normal mitochondrial function is preserved by several interrelated mechanisms. One mechanism - intramitochondrial quality control (IMQC) - is represented by conserved proteases distributed across mitochondrial compartments. Many aspects and physiological roles of IMQC components remain unclear....

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Source

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Identifiers

PMID: 26365306
DOI: 10.1038/srep13989
PMCID: PMC4568518

Genes

OMA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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