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Article

Control of mitochondrial integrity in ageing and disease.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Jul 2014

Szklarczyk Radek, Nooteboom Marco, Osiewacz Heinz D

Abstract excerpt

Various molecular and cellular pathways are active in eukaryotes to control the quality and integrity of mitochondria. These pathways are involved in keeping a 'healthy' population of this essential organelle during the lifetime of the organism. Quality control (QC) systems counteract processes that lead to organellar dysfunction manifesting as degenerative diseases and ageing. We discuss disease- and...

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Identifiers

PMID: 24864310
DOI: 10.1098/rstb.2013.0439
PMCID: PMC4032516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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