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Article

Multi-omic Mitoprotease Profiling Defines a Role for Oct1p in Coenzyme Q Production.

Molecular cell - 7 Dec 2017

Veling Mike T, Reidenbach Andrew G, Freiberger Elyse C, Kwiecien Nicholas W, Hutchins Paul D, Drahnak Michael J, Jochem Adam, Ulbrich Arne, Rush Matthew J P, Russell Jason D, Coon Joshua J, Pagliarini David J

Abstract excerpt

Mitoproteases are becoming recognized as key regulators of diverse mitochondrial functions, although their direct substrates are often difficult to discern. Through multi-omic profiling of diverse Saccharomyces cerevisiae mitoprotease deletion strains, we predicted numerous associations between mitoproteases and distinct mitochondrial processes. These include a strong association between the mitochondrial matrix...

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Identifiers

PMID: 29220658
DOI: 10.1016/j.molcel.2017.11.023
PMCID: PMC5730362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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