Article
Exploring the Oxidation of Lignin-Derived Phenols by a Library of Laccase Mutants.
Molecules (Basel, Switzerland) - 2 Sept 2015
Pardo Isabel, Camarero Susana
Abstract excerpt
Saturation mutagenesis was performed over six residues delimiting the substrate binding pocket of a fungal laccase previously engineered in the lab. Mutant libraries were screened using sinapic acid as a model substrate, and those mutants presenting increased activity were selected for exploring the oxidation of lignin-derived phenols. The latter comprised a battery of phenolic compounds of interest due to their...
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