Pleiotropic analysis of cancer risk loci on esophageal adenocarcinoma risk.

doi:10.1158/1055-9965.EPI-15-0596

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Article

Pleiotropic analysis of cancer risk loci on esophageal adenocarcinoma risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2015

Lee Eunjung, Stram Daniel O, Ek Weronica E, Onstad Lynn E, MacGregor Stuart, Gharahkhani Puya, Ye Weimin, Lagergren Jesper, Shaheen Nicholas J, Murray Liam J, Hardie Laura J, Gammon Marilie D, Chow Wong-Ho, Risch Harvey A, Corley Douglas A, Levine David M, Whiteman David C, Bernstein Leslie, Bird Nigel C, Vaughan Thomas L, Wu Anna H

Abstract excerpt

BACKGROUND: Several cancer-associated loci identified from genome-wide association studies (GWAS) have been associated with risks of multiple cancer sites, suggesting pleiotropic effects. We investigated whether GWAS-identified risk variants for other common cancers are associated with risk of esophageal adenocarcinoma (EA) or its precursor, Barrett's esophagus. METHODS: We examined the associations between risks...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26364162
DOI: 10.1158/1055-9965.EPI-15-0596
PMCID: PMC4648999

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