Article
Two novel variants on 13q22.1 are associated with risk of esophageal squamous cell carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2015
Chang Jiang, Wei Lixuan, Miao Xiaoping, Yu Dianke, Tan Wen, Zhang Xuemei, Wu Chen, Lin Dongxin
Abstract excerpt
BACKGROUND: Chromosome 13q22.1 has previously been identified to be a susceptibility locus for pancreatic cancer in Chinese and European ancestry populations. This pleiotropy study aimed to identify novel variants in this region associated with susceptibility to different types of human cancer. METHOD: To fine-map the 13q22.1 region, imputation analyses were conducted on the basis of the GWAS data of 2,031...
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