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Article

Common Variants of the Prostaglandin-Endoperoxide Synthase 2 Gene and Hepatocellular Carcinoma Susceptibility.

Medicine - 1 Sept 2015

Li Hong-Guang, Liu Fang-Feng, Zhu Hua-Qiang, Zhou Xu, Lu Jun, Chang Hong, Hu Jin-Hua

Abstract excerpt

Hepatocellular carcinoma (HCC) is a heterogeneous disease with substantial genetic constitution. Previous work has evaluated the effect of prostaglandin-endoperoxide synthase 2 (PTGS2) variants (-765G/C, -1195A/G, and +8473T/C) on the development of HCC, but the conclusions are inconsistent. We conducted a meta-analysis in this work. Data from 7 case-control studies were combined to assess the association between...

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Source

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Identifiers

PMID: 26334888
DOI: 10.1097/MD.0000000000001116
PMCID: PMC4616504

Genes

PTGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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