Article
Association of cyclooxygenase 2 single-nucleotide polymorphisms and hepatocellular carcinoma in Taiwan.
The Chinese journal of physiology - 29 Feb 2012
Chang Wen-Shin, Yang Mei-Due, Tsai Chia-Wen, Cheng Li-Hao, Jeng Long-Bin, Lo Woei-Chung, Lin Chih-Hsueh, Huang Chih-Yang, Bau Da-Tian
Abstract excerpt
Hepatocellular carcinoma (HCC) is a worldwide neoplasm for which early diagnosis is difficult and the prognosis is usually poor. Overexpression of cyclooxygenase 2 (COX-2) has been suggested to be associated with hepatocarcinogenesis. Although several COX-2 inhibitors have been used in hepatoma therapy, the genetic background between COX-2 and HCC remains largely unknown. In this study, the association of...
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