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Article

The association between three cyclooxygenase-2 polymorphisms and hepatocellular carcinoma risk: a meta-analysis.

PloS one - 1 Jan 2015

Chen Zhigang, Zhu Jiye, Huang Chaoyuan, Lian Fang, Wu Guobin, Zhao Yinnong

Abstract excerpt

BACKGROUND: A quantity of case-control studies have been performed to address the association between three cyclooxygenase-2(COX-2) polymorphisms (-1195G/A, -765G/C and +8473T/C) and the risk of hepatocellular carcinoma (HCC). However, previous research results are inconsistent. We conducted this meta-analysis to clarify the correlation between these COX-2 polymorphisms and HCC risk. METHODS: The authors searched...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25730260
DOI: 10.1371/journal.pone.0118251
PMCID: PMC4346398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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