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Article

Cyclooxygenase-2 gene polymorphisms and susceptibility to hepatocellular carcinoma: A meta-analysis based on 10 case-control studies.

Journal of cancer research and therapeutics - 1 Jan 2018

Xu Wei, Huang Yaping, Zhang Ting, Zhao Lingyun, Fan Jun, Li Lanjuan

Abstract excerpt

OBJECTIVE: The association between cyclooxygenase-2 (COX-2) gene polymorphisms and hepatocellular carcinoma (HCC) has been widely reported, but the results are still controversial. To clarify the effect of COX-2 -1195G/A (rs689466), -765G/C (rs20417), and +8473T/C (rs5275) polymorphisms on HCC risk, a meta-analysis was performed. MATERIALS AND METHODS: The PubMed, Embase, Cochrane Library, Web of Science, Chinese...

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Identifiers

PMID: 29578159
DOI: 10.4103/0973-1482.172110

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