Article
Cyclooxygenase-2 gene and epithelial ovarian carcinoma risk.
Molecular biology reports - 1 Jun 2011
Agachan Cakmakoglu Bedia, Attar Rukset, Kahraman Ozlem Timirci, Dalan Altay Burak, Iyibozkurt Ahmet Cem, Karateke Ates, Attar Erkut
Abstract excerpt
In this study, we aimed to investigate a possible association of the COX-2 polymorphisms (-765G→C and -1195A→G) and with the risk of developing epithelial ovarian carcinoma (EOC). COX-2 gene polymorphisms was investigated in 111 healthy women and 57 patients with EOC. Individuals who had -765 CG, -1195 AA genotype, and -765 C allele had increased risk for ovarian carcinoma (P < 0.01) and individuals with -765 GG,...
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