Article
Functional polymorphisms of the cyclooxygenase (PTGS2) gene and risk for gallbladder cancer in a North Indian population.
Journal of gastroenterology - 1 Jan 2009
Srivastava Kshitij, Srivastava Anvesha, Pandey Sachchida Nand, Kumar Ashok, Mittal Balraj
Abstract excerpt
BACKGROUND: Cyclooxygenase-2 (PTGS2) overexpression has been implicated in various cancers. We aimed to evaluate the role of PTGS2 -1195G>A [reference sequence (rs) 689466], -765G>C (rs20417) and +8473T>C (rs5275) polymorphisms in conferring interindividual susceptibility to gallbladder cancer. MATERIALS AND METHODS: The study included 167 gallbladder cancer cases and 184 controls. Genotyping was done by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
