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Article

Exploring the cellular basis of human disease through a large-scale mapping of deleterious genes to cell types.

Genome medicine - 1 Sept 2015

Cornish Alex J, Filippis Ioannis, David Alessia, Sternberg Michael J E

Abstract excerpt

BACKGROUND: Each cell type found within the human body performs a diverse and unique set of functions, the disruption of which can lead to disease. However, there currently exists no systematic mapping between cell types and the diseases they can cause. METHODS: In this study, we integrate protein-protein interaction data with high-quality cell-type-specific gene expression data from the FANTOM5 project to build...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26330083
DOI: 10.1186/s13073-015-0212-9
PMCID: PMC4557825

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GSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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