Article

Integrated molecular, clinical, and ontological analysis identifies overlooked disease relationships

2017-11-06

Abstract excerpt

Existing knowledge of human disease relationships is incomplete. To establish a comprehensive understanding of disease, we integrated transcriptome profiles of 41,000 human samples with clinical profiles of 2 million patients, across 89 diseases. Based on transcriptome data, autoimmune diseases clustered with their specific infectious triggers, and brain disorders clustered by disease class. Clinical profiles clus...

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Identifiers and source

Literature Corpus work: 865a247b-24f4-5dff-9cd6-04197fd1a147
DOI: 10.1101/214833

Open publication

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