Article

HCNetlas: Human cell network atlas enabling cell type-resolved disease genetics

2024-06-09

Abstract excerpt

Cell type-specific actions of disease genes add a significant layer of complexity to the genetic architecture underlying diseases, obscuring our understanding of disease mechanisms. Single-cell omics have revealed the functional roles of genes at the cellular level, identifying cell types critical for disease progression. Often, a gene impact on disease through its altered network within specific cell types, rathe...

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Literature Corpus work: 0c1ba8f5-997b-5f1b-a08f-65e9a03bc88e
DOI: 10.1101/2024.06.07.597878

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