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Article

Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system.

Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 2015

Gailite Ieva, Aerne Birgit L, Tapon Nicolas

Abstract excerpt

The Hippo (Hpo) pathway is a highly conserved tumor suppressor network that restricts developmental tissue growth and regulates stem cell proliferation and differentiation. At the heart of the Hpo pathway is the progrowth transcriptional coactivator Yorkie [Yki-Yes-activated protein (YAP)/transcr...

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Identifiers

PMID: 26324895
DOI: 10.1073/pnas.1505512112
PMCID: PMC4577147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26324895-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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