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Article

Functional diversity of CTCFs is encoded in their binding motifs.

BMC genomics - 28 Aug 2015

Fang Rongxin, Wang Chengqi, Skogerbo Geir, Zhang Zhihua

Abstract excerpt

BACKGROUND: The CCCTC-binding factor (CTCF) has diverse regulatory functions. However, the definitive characteristics of the CTCF binding motif required for its functional diversity still remains elusive. RESULTS: Here, we describe a new motif discovery workflow by which we have identified three CTCF binding motif variations with highly divergent functionalities. Supported by transcriptomic, epigenomic and...

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Identifiers

PMID: 26315019
DOI: 10.1186/s12864-015-1824-6
PMCID: PMC4552278

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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