Article

Clustering of Direct and Indirect DNA Binding Motifs of Human and Mouse Transcription Factors: X-TFBS Compendium from ChIP-seq

2025-11-11

Abstract excerpt

Uncovering networks of gene expression regulation requires knowledge of specific DNA-binding motifs of transcription factors (TFs). Most TFs have multiple DNA motifs enriched in its ChIP-seq peak regions because of protein interaction and spatial correlation between TFs and cofactors. To capture both direct binding and indirect association of TFs with specific DNA locations, all-against-all relations are identifie...

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Literature Corpus work: 4ee2e176-943e-5dd8-a337-10180e294c02
DOI: 10.1101/2025.11.09.687492

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