Article
Polymorphisms of the beta1-adrenergic receptor gene are associated with essential hypertension in Chinese.
Clinical chemistry and laboratory medicine - 1 Jan 2009
Peng Yingxin, Xue Hao, Luo Leiming, Yao Wenjing, Li Rongbin
Abstract excerpt
BACKGROUND: The beta1-adrenergic receptor (ADRB1) plays a pivotal role in mediating signal transduction of the sympathetic-adrenal system, which is involved in the regulation of cardiac output and peripheral resistance. Our goal was to determine whether the polymorphisms Arg389Gly (rs1801253) and Ser49Gly (rs1801252) of the ADRB1 gene were associated with essential hypertension in Chinese. METHODS: We tested our...
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