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Article

Polymorphism in the beta(1)-adrenergic receptor gene and hypertension.

Circulation - 10 Jul 2001

Bengtsson K, Melander O, Orho-Melander M, Lindblad U, Ranstam J, Råstam L, Groop L

Abstract excerpt

BACKGROUND: The Arg389 variant of the beta(1)-adrenergic receptor gene mediates a higher isoproterenol-stimulated adenylate cyclase activity than the Gly389 variant in vitro. We investigated whether the Arg389Gly or the Ser49Gly polymorphism is associated with hypertension in Scandinavians. Methods and Results-- A total of 292 unrelated, nondiabetic, hypertensive patients and 265 unrelated healthy control...

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Identifiers

PMID: 11447084
DOI: 10.1161/01.cir.104.2.187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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