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Article

Genetic Evidence for Differential Regulation of Corneal Epithelial and Stromal Thickness.

Investigative ophthalmology & visual science - 1 Aug 2015

Koehn Demelza R, Meyer Kacie J, Anderson Michael G

Abstract excerpt

PURPOSE: Central corneal thickness (CCT) is a quantitative trait associated with keratoconus and primary open-angle glaucoma. Although CCT is highly heritable, known genetic variations explain only a fraction of the phenotypic variability. The purpose of this study was to identify additional CCT-influencing loci using inbred strains of mice. METHODS: Cohorts of 82 backcrossed (N2) and 99 intercrossed (F2) mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26305532
DOI: 10.1167/iovs.15-17179
PMCID: PMC4553932

Genes

CAST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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