Article

<i>Tyr</i> is Responsible for the <i>Cctq1a</i> QTL and Links Developmental Environment to Central Corneal Thickness Determination

2021-09-24

Abstract excerpt

Central corneal thickness is a quantitative trait with important associations to human health. In a phenotype-driven approach studying corneal thickness of congenic derivatives of C57BLKS/J and SJL/J mice, the critical region for a quantitative trait locus influencing corneal thickness, Cctq1a , was delimited to a 10-gene interval. Exome sequencing, RNAseq, and studying independent mutations eliminated multiple c...

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Literature Corpus work: 03048432-6aa7-5859-a21a-d61302a3c236
DOI: 10.1101/2021.09.22.461410

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