Article
Anterior chamber depth in mice is controlled by several quantitative trait loci.
PloS one - 1 Jan 2023
Larson Demelza R, Kimber Allysa J, Meyer Kacie J, Anderson Michael G
Abstract excerpt
Anterior chamber depth (ACD) is a quantitative trait associated with primary angle closure glaucoma (PACG). Although ACD is highly heritable, known genetic variations explain a small fraction of the phenotypic variability. The purpose of this study was to identify additional ACD-influencing loci using strains of mice. Cohorts of 86 N2 and 111 F2 mice were generated from crosses between recombinant inbred...
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