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Article

Pathway-Based Genome-wide Association Studies Reveal That the Rac1 Pathway Is Associated with Plasma Adiponectin Levels.

Scientific reports - 24 Aug 2015

Li Wei-Dong, Jiao Hongxiao, Wang Kai, Yang Fuhua, Grant Struan F A, Hakonarson Hakon, Ahima Rexford, Arlen Price R

Abstract excerpt

Pathway-based analysis as an alternative and effective approach to identify disease-related genes or loci has been verified. To decipher the genetic background of plasma adiponectin levels, we performed genome wide pathway-based association studies in extremely obese individuals and normal-weight controls. The modified Gene Set Enrichment Algorithm (GSEA) was used to perform the pathway-based analyses (the GenGen...

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Identifiers

PMID: 26299439
DOI: 10.1038/srep13422
PMCID: PMC4642532

Genes

RAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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