Article
Comparison of methods for competitive tests of pathway analysis.
PloS one - 1 Jan 2012
Evangelou Marina, Rendon Augusto, Ouwehand Willem H, Wernisch Lorenz, Dudbridge Frank
Abstract excerpt
It has been suggested that pathway analysis can complement single-SNP analysis in exploring genomewide association data. Pathway analysis incorporates the available biological knowledge of genes and SNPs and is expected to improve the chances of revealing the underlying genetic architecture of complex traits. Methods for pathway analysis can be classified as competitive (enrichment) or self-contained...
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