Article

Deletion of CD44 promotes adipogenesis by regulating PPARɣ and cell cycle-related pathways

2023-10-13

Abstract excerpt

CD44, a cell surface adhesion receptor and stem cell biomarker, is recently implicated in chronic metabolic diseases. Ablation of CD44 ameliorates adipose tissue inflammation and insulin resistance in obesity. Here, we investigated cell type specific CD44 expression in human and mouse adipose tissue and further studied how CD44 in preadipocytes regulates adipocyte function. Using Crispr Cas9-mdediated gene deletio...

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Identifiers and source

Literature Corpus work: 83060086-2cd5-5633-9782-9256fc72236a
DOI: 10.1101/2023.10.13.562173

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