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Article

Pathway-based genome-wide association analysis of coronary heart disease identifies biologically important gene sets.

European journal of human genetics : EJHG - 1 Nov 2012

de las Fuentes Lisa, Yang Wei, Dávila-Román Victor G, Gu C Charles

Abstract excerpt

Genome-wide association (GWA) studies of complex diseases including coronary heart disease (CHD) challenge investigators attempting to identify relevant genetic variants among hundreds of thousands of markers being tested. A selection strategy based purely on statistical significance will result in many false negative findings after adjustment for multiple testing. Thus, an integrated analysis using information...

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Identifiers

PMID: 22510845
DOI: 10.1038/ejhg.2012.66
PMCID: PMC3477866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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