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Article

Pathway-Based Genome-Wide Association Studies for Plasma Triglycerides in Obese Females and Normal-Weight Controls.

PloS one - 1 Jan 2015

Jiao Hongxiao, Wang Kai, Yang Fuhua, Grant Struan F A, Hakonarson Hakon, Price R Arlen, Li Wei-Dong

Abstract excerpt

Pathway-based analysis as an alternative approach can provide complementary information to single-marker genome-wide association studies (GWASs), which always ignore the epistasis and does not have sufficient power to find rare variants. In this study, using genotypes from a genome-wide association study (GWAS), pathway-based association studies were carried out by a modified Gene Set Enrichment Algorithm (GSEA)...

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Source

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Identifiers

PMID: 26308950
DOI: 10.1371/journal.pone.0134923
PMCID: PMC4550433

Genes

ASTN2
BCL6
ABCG1
MMAB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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