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Article

CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study.

American journal of hypertension - 1 Apr 2016

Ackermann Daniel, Pruijm Menno, Ponte Belen, Guessous Idris, Ehret Georg, Escher Geneviève, Dick Bernhard, Al-Alwan Heba, Vuistiner Philippe, Paccaud Fred, Burnier Michel, Péchère-Bertschi Antoinette, Martin Pierre-Yves, Vogt Bruno, Mohaupt Markus, Bochud Murielle

Abstract excerpt

BACKGROUND: Genome-wide association studies have linked CYP17A1 coding for the steroid hormone synthesizing enzyme 17α-hydroxylase (CYP17A1) to blood pressure (BP). We hypothesized that the genetic signal may translate into a correlation of ambulatory BP (ABP) with apparent CYP17A1 activity in a family-based population study and estimated the heritability of CYP17A1 activity. METHODS: In the Swiss Kidney Project...

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Identifiers

PMID: 26297028
DOI: 10.1093/ajh/hpv138
PMCID: PMC4886492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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