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Article

Association of CYP3A5 genotypes with blood pressure and renal function in African families.

Journal of hypertension - 1 May 2006

Bochud Murielle, Eap Chin B, Elston Robert C, Bovet Pascal, Maillard Marc, Schild Laurent, Shamlaye Conrad, Burnier Michel

Abstract excerpt

OBJECTIVE: Renal cytochrome P450 3A5 (CYP3A5) activity has been associated with blood pressure and salt sensitivity in humans. We determined whether CYP3A5 polymorphisms are associated with ambulatory blood pressure (ABP) and with glomerular filtration rate (GFR) in African families. METHODS: Using a cross-sectional design, 375 individuals from 72 families, each with at least two hypertensive siblings, were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16612255
DOI: 10.1097/01.hjh.0000222763.84605.4a

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