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Article

Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.

The Journal of clinical endocrinology and metabolism - 1 Dec 2006

Imrie Helen, Freel Marie, Mayosi Bongani M, Davies Eleanor, Fraser Robert, Ingram Mary, Cordell Heather J, Farrall Martin, Avery Peter J, Watkins Hugh, Keavney Bernard, Connell John M C

Abstract excerpt

CONTEXT: Variation in the region of chromosome 8 including the genes steroid 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) influences mineralocorticoid and glucocorticoid metabolism. However, the relative importance of polymorphisms in CYP11B1 and CYP11B2 in determining these phenotypes is unknown. OBJECTIVE: Our objective was to investigate genetic influences of the CYP11B1 and CYP11B2 genes on...

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Identifiers

PMID: 16984984
DOI: 10.1210/jc.2006-1481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between aldosterone production and variation in the 11beta-hydroxylase (CYP11B1) gene.PMID 16984984Read ↗

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The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.Semantic proximity Read ↗

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