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Article

GSTP1 Polymorphisms and their Association with Glutathione Transferase and Peroxidase Activities in Patients with Motor Neuron Disease.

CNS & neurological disorders drug targets - 1 Jan 2015

Gajewska Beata, Kaźmierczak Beata, Kuźma-Kozakiewicz Magdalena, Jamrozik Zygmunt, Barańczyk-Kuźma Anna

Abstract excerpt

Glutathione S-transferase pi (GSTP1) is a crucial enzyme in detoxification of electrophilic compounds and organic peroxides. Together with Se-dependent glutathione peroxidase (Se-GSHPx) it protects cells against oxidative stress which may be a primary factor implicated in motor neuron disease (MND) pathogenesis. We investigated GSTP1 polymorphisms and their relationship with GST and Se-GSTPx activities in a...

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Source

Identifiers

PMID: 26295823
DOI: 10.2174/1871527314666150821104019

Genes

GSTP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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