Article
Parkinson's disease, pesticides, and glutathione transferase polymorphisms.
Lancet (London, England) - 24 Oct 1998
Menegon A, Board P G, Blackburn A C, Mellick G D, Le Couteur D G
Abstract excerpt
BACKGROUND: Parkinson's disease is thought to be secondary to the presence of neurotoxins, and pesticides have been implicated as possible causative agents. Glutathione transferases (GST) metabolise xenobiotics, including pesticides. Therefore, we investigated the role of GST polymorphisms in the...
Topics
- Aged
- Australia
- Blood-Brain Barrier
- Case-Control Studies
- Environmental Exposure
- Female
- Genotype
- Glutathione Transferase
- Humans
- Logistic Models
- Male
- Middle Aged
- Parkinson Disease, Secondary
- Pesticides
- Polymorphism, Genetic
- Surveys and Questionnaires