Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parkinson's disease, pesticides, and glutathione transferase polymorphisms.

Lancet (London, England) - 24 Oct 1998

Menegon A, Board P G, Blackburn A C, Mellick G D, Le Couteur D G

Abstract excerpt

BACKGROUND: Parkinson's disease is thought to be secondary to the presence of neurotoxins, and pesticides have been implicated as possible causative agents. Glutathione transferases (GST) metabolise xenobiotics, including pesticides. Therefore, we investigated the role of GST polymorphisms in the pathogenesis of idiopathic Parkinson's disease. METHODS: We genotyped by PCR polymorphisms in four GST classes (GSTM1,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Australia
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GSTM1 gene

Share to Genotype

Share to Glutathione Transferase

Share to Logistic Models

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 9802272
DOI: 10.1016/s0140-6736(98)03453-9

Genes

GSTP1
GSTM1
GSTT1
GSTZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parkinson's disease, pesticides, and glutathione transferase polymorphisms.PMID 9802272Read ↗

Nullity of GSTT1/GSTM1 related to pesticides is associated with Parkinson's disease.Semantic proximity Read ↗

Parkinson's disease and pesticides: A meta-analysis of disease connection and genetic alterations.Semantic proximity Read ↗

Pesticide-induced gene mutations and Parkinson disease risk: a meta-analysis.Semantic proximity Read ↗

Pesticides and Parkinson's disease.Semantic proximity Read ↗

MDR1 variants and risk of Parkinson disease. Association with pesticide exposure?Semantic proximity Read ↗

Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease.Semantic proximity Read ↗

Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease.Semantic proximity Read ↗

Interaction between ABCB1 and professional exposure to organochlorine insecticides in Parkinson disease.Semantic proximity Read ↗

Association of Paraoxonse1 (PON1) Genotypes with the Activity of PON1 in Patients with Parkinson's Disease.Semantic proximity Read ↗

Parkinson's disease, pesticides and mitochondrial dysfunctionSemantic proximity Read ↗

The interplay between environmental and genetic factors in Parkinson's disease susceptibility: the evidence for pesticides.Semantic proximity Read ↗

Neurotoxicity of pesticides – A link to neurodegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.