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Article

GSTP1 gene Ile105Val polymorphism causes an elevated risk for bladder carcinogenesis in smokers.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Pandith Arshad Ahmad, Lateef Adil, Shahnawaz Sheikh, Hussain Aashaq, Malla Tahir Mohiuddin, Azad Niyaz, Shehjar Fahim, Salim Mosin, Shah Zafar Amin

Abstract excerpt

BACKGROUND: The glutathione S transferase (GST) family of enzymes plays a vital role in the phase II biotransformation of environmental carcinogens, pollutants, drugs and other xenobiotics. GSTs are polymorphic and polymorphisms in GST genes have been associated with cancer susceptibility and prognosis. GSTP1 is associated with risk of various cancers including bladder cancer. A case control study was conducted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24377535
DOI: 10.7314/apjcp.2013.14.11.6375

Genes

GSTP1
UBC

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