Article
Epidemiological, clinical, and molecular study of a cohort of Italian Parkinson disease patients: association with glutathione-S-transferase and DNA repair gene polymorphisms.
Cellular and molecular neurobiology - 1 Jul 2013
Cornetta Tommaso, Patrono Clarice, Terrenato Irene, De Nigris Francesca, Bentivoglio Anna Rita, Testa Antonella, Palma Valentina, Poggioli Tommaso, Padua Luca, Cozzi Renata
Abstract excerpt
Parkinson's disease (PD) is one of the most common neurodegenerative disorders whose etiology is multifactorial including both hereditary and environmental factors. Currently, pathogenic mutations in at least five genes have been implicated in familial PD generally accounting for less than 10 % of all PD cases in most populations. It has been suggested that polymorphisms in other genes such as those encoding...
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